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Bicoid-Dependent Activation of the Target Gene hunchback Requires a Two-Motif Sequence Code in a Specific Basal Promoter

In complex genetic loci, individual enhancers interact most often with specific basal promoters. Here we investigate the activation of the Bicoid target gene hunchback (hb), which contains two basal promoters (P1 and P2). Early in embryogenesis, P1 is silent, while P2 is strongly activated. In vivo...

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Detalles Bibliográficos
Publicado en:Mol Cell
Main Authors: Ling, Jia, Umezawa, Kristaley Yui, Scott, Theresa, Small, Stephen
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754290/
https://ncbi.nlm.nih.gov/pubmed/31402096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.06.038
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