Betulinic Acid Enhances the Viability of Random-Pattern Skin Flaps by Activating Autophagy

Random-pattern skin flap replantation is commonly used to repair skin defects during plastic and reconstructive surgery. However, flap necrosis due to ischemia and ischemia–reperfusion injury limits clinical applications. Betulinic acid, a plant-derived pentacyclic triterpene, may facilitate flap su...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Front Pharmacol
Autori principali: Li, Jiafeng, Bao, Guodong, ALyafeai, Eman, Ding, Jian, Li, Shihen, Sheng, Shimin, Shen, Zitong, Jia, Zhenyu, Lin, Chen, Zhang, Chenxi, Lou, Zhiling, Xu, Huazi, Gao, Weiyang, Zhou, Kailiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6753397/
https://ncbi.nlm.nih.gov/pubmed/31572190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01017
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