Loading...

IgA-deficient humans exhibit gut microbiota dysbiosis despite secretion of compensatory IgM

Immunoglobulin A is the dominant antibody isotype found in mucosal secretions and enforces host-microbiota symbiosis in mice, yet selective IgA-deficiency (sIgAd) in humans is often described as asymptomatic. Here, we determined the effects of IgA deficiency on human gut microbiota composition and e...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Catanzaro, Jason R., Strauss, Juliet D., Bielecka, Agata, Porto, Anthony F., Lobo, Francis M., Urban, Andrea, Schofield, Whitman B., Palm, Noah W.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6753154/
https://ncbi.nlm.nih.gov/pubmed/31537840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49923-2
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!