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IgA-deficient humans exhibit gut microbiota dysbiosis despite secretion of compensatory IgM
Immunoglobulin A is the dominant antibody isotype found in mucosal secretions and enforces host-microbiota symbiosis in mice, yet selective IgA-deficiency (sIgAd) in humans is often described as asymptomatic. Here, we determined the effects of IgA deficiency on human gut microbiota composition and e...
Enregistré dans:
| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6753154/ https://ncbi.nlm.nih.gov/pubmed/31537840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49923-2 |
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