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Photopharmacologic Vision Restoration Reduces Pathological Rhythmic Field Potentials in Blind Mouse Retina

Photopharmacology has yielded compounds that have potential to restore impaired visual responses resulting from outer retinal degeneration diseases such as retinitis pigmentosa. Here we evaluate two photoswitchable azobenzene ion channel blockers, DAQ and DAA for vision restoration. DAQ exerts its e...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hüll, Katharina, Benster, Tyler, Manookin, Michael B., Trauner, Dirk, Van Gelder, Russell N., Laprell, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6753071/
https://ncbi.nlm.nih.gov/pubmed/31537864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49999-w
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