Suppressive impact of metronomic chemotherapy using UFT and/or cyclophosphamide on mediators of breast cancer dissemination and invasion

Metronomic chemotherapy using the 5-FU prodrug uracil-tegafur (UFT) and cyclophosphamide (CTX) was previously shown to only modestly delay primary tumor growth, but nevertheless markedly suppressed the development of micro-metastasis in an orthotopic breast cancer xenograft model, using the metastat...

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Vydáno v:PLoS One
Hlavní autoři: Muñoz, Raquel, Hileeto, Denise, Cruz-Muñoz, William, Wood, Geoffrey A., Xu, Ping, Man, Shan, Viloria-Petit, Alicia, Kerbel, Robert S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6752870/
https://ncbi.nlm.nih.gov/pubmed/31536574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0222580
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