Molecular basis of dengue virus serotype 2 morphological switch from 29°C to 37°C

The ability of DENV2 to display different morphologies (hence different antigenic properties) complicates vaccine and therapeutics development. Previous studies showed most strains of laboratory adapted DENV2 particles changed from smooth to “bumpy” surfaced morphology when the temperature is switch...

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Sparad:
Bibliografiska uppgifter
I publikationen:PLoS Pathog
Huvudupphovsmän: Lim, Xin-Ni, Shan, Chao, Marzinek, Jan K., Dong, Hongping, Ng, Thiam Seng, Ooi, Justin S. G., Fibriansah, Guntur, Wang, Jiaqi, Verma, Chandra S., Bond, Peter J., Shi, Pei-Yong, Lok, Shee-mei
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2019
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6752767/
https://ncbi.nlm.nih.gov/pubmed/31536610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007996
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