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Immature and Mature Dengue Serotype 1 Virus Structures Provide Insight into the Maturation Process

Dengue virus is a major human pathogen that has four serotypes (DENV1 to -4). Here we report the cryoelectron microscopy (cryo-EM) structures of immature and mature DENV1 at 6- and 4.5-Å resolution, respectively. The subnanometer-resolution maps allow accurate placement of all of the surface protein...

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Detalhes bibliográficos
Main Authors: Kostyuchenko, Victor A., Zhang, Qian, Tan, Joanne L., Ng, Thiam-Seng, Lok, Shee-Mei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700294/
https://ncbi.nlm.nih.gov/pubmed/23637416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00197-13
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