Cargando...
Impact of NUDT15 genetics on severe thiopurine-related hematotoxicity in patients with European ancestry
PURPOSE: Severe hematotoxicity in patients with thiopurine therapy has been associated with genetic polymorphisms in the thiopurine S-methyltransferase (TPMT). While TPMT genetic testing is clinically implemented for dose individualization, alterations in the nudix hydrolase 15 (NUDT15) emerged as i...
Guardado en:
| Publicado en: | Genet Med |
|---|---|
| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group US
2019
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6752748/ https://ncbi.nlm.nih.gov/pubmed/30728528 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41436-019-0448-7 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|