Chargement en cours...

Redox State Controls Phase Separation of the Yeast Ataxin-2 Protein via Reversible Oxidation of its Methionine-Rich Low Complexity Domain

Yeast ataxin-2, also known as Pbp1, senses the activity state of mitochondria in order to regulate TORC1. A domain of Pbp1 required to adapt cells to mitochondrial activity is of low sequence complexity. The low complexity (LC) domain of Pbp1 forms labile, cross-β polymers that facilitate phase tran...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Cell
Auteurs principaux: Kato, Masato, Yang, Yu-San, Sutter, Benjamin M., Wang, Yun, McKnight, Steven L., Tu, Benjamin P.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6752730/
https://ncbi.nlm.nih.gov/pubmed/30982603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.02.044
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!