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OGDH promotes the progression of gastric cancer by regulating mitochondrial bioenergetics and Wnt/β-catenin signal pathway

BACKGROUND/AIMS: 2-oxoglutarate dehydrogenase (OGDH) is the first rate-limiting E1 subunit of OGDH complex (OGDHC), which plays as a regulatory point in the cross-road of TCA cycle and glutamine metabolism. Until now, the role of OGDH in carcinogenesis has been unclear. METHODS: In the present study...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Lu, Xin, Wu, Nan, Yang, Wanli, Sun, Jia, Yan, Kemin, Wu, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6752206/
https://ncbi.nlm.nih.gov/pubmed/31686854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S208848
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