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Wnt/β-catenin promotes gastric fundus specification in mice and humans

Despite the global prevalence of gastric disease, there are few adequate models to study the fundus epithelium of the human stomach. We differentiated human pluripotent stem cells (PSCs) into gastric organoids containing fundic epithelium by first identifying and then recapitulating key events in em...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Nature
Päätekijät: McCracken, Kyle W., Zhang, Xinghao, Wells, James M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526592/
https://ncbi.nlm.nih.gov/pubmed/28052057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature21021
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