Evolution of resistance mechanisms and biological characteristics of rifampicin-resistant Staphylococcus aureus strains selected in vitro

BACKGROUND: We aimed to determine the evolutionary pathways of rifampicin resistance in Staphylococcus aureus, and the impact of resistance mutations in the rpoB gene on fitness. METHODS: Three clinical strains and one reference strain were used to select for rifampicin-resistant S. aureus variants....

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Bibliografiske detaljer
Udgivet i:BMC Microbiol
Main Authors: Wang, Chong, Fang, Renchi, Zhou, Beibei, Tian, Xuebin, Zhang, Xiucai, Zheng, Xiangkuo, Zhang, Siqin, Dong, Guofeng, Cao, Jianming, Zhou, Tieli
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6751903/
https://ncbi.nlm.nih.gov/pubmed/31533633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-019-1573-9
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