A20 protects cells from TNF-induced apoptosis through linear ubiquitin-dependent and -independent mechanisms

The cytokine TNF promotes inflammation either directly by activating the MAPK and NF-κB signaling pathways, or indirectly by triggering cell death. A20 is a potent anti-inflammatory molecule, and mutations in the gene encoding A20 are associated with a wide panel of inflammatory pathologies, both in...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Priem, Dario, Devos, Michael, Druwé, Sarah, Martens, Arne, Slowicka, Karolina, Ting, Adrian T., Pasparakis, Manolis, Declercq, Wim, Vandenabeele, Peter, van Loo, Geert, Bertrand, Mathieu J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6751190/
https://ncbi.nlm.nih.gov/pubmed/31534131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1937-y
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