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Optineurin Functions for Optimal Immunity

Optineurin (OPTN) was identified 20 years ago in a yeast-two-hybrid screen with a viral protein known to inhibit the cytolytic effects of tumor necrosis factor. Since then, OPTN has been identified as a ubiquitin-binding protein involved in many signaling pathways and cellular processes, and mutatio...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Slowicka, Karolina, van Loo, Geert
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902560/
https://ncbi.nlm.nih.gov/pubmed/29692786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00769
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