Tau Phosphorylation and Aggregation in the Developing Human Brain

Tau hyperphosphorylation, mostly at serine (Ser) or threonine (Thr) residues, plays a key role in the pathogenesis of Alzheimer disease (AD) and other tauopathies. Rodent studies show similar hyperphosphorylation in the developing brain, which may be involved in regulating axonal growth and plastici...

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Detalhes bibliográficos
Publicado no:J Neuropathol Exp Neurol
Main Authors: Hefti, Marco M, Kim, SoongHo, Bell, Aaron J, Betters, Ryan K, Fiock, Kimberly L, Iida, Megan A, Smalley, Martin E, Farrell, Kurt, Fowkes, Mary E, Crary, John F
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6751069/
https://ncbi.nlm.nih.gov/pubmed/31504677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlz073
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