Tau Phosphorylation and Aggregation in the Developing Human Brain

Tau hyperphosphorylation, mostly at serine (Ser) or threonine (Thr) residues, plays a key role in the pathogenesis of Alzheimer disease (AD) and other tauopathies. Rodent studies show similar hyperphosphorylation in the developing brain, which may be involved in regulating axonal growth and plastici...

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Veröffentlicht in:J Neuropathol Exp Neurol
Hauptverfasser: Hefti, Marco M, Kim, SoongHo, Bell, Aaron J, Betters, Ryan K, Fiock, Kimberly L, Iida, Megan A, Smalley, Martin E, Farrell, Kurt, Fowkes, Mary E, Crary, John F
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6751069/
https://ncbi.nlm.nih.gov/pubmed/31504677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlz073
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