Epigenetic inhibition of the tumor suppressor ARHI by light at night-induced circadian melatonin disruption mediates STAT3-driven paclitaxel resistance in breast cancer

Disruption of circadian time structure and suppression of circadian nocturnal melatonin (MLT) production by exposure to dim light at night (dLAN), as occurs with night shift work and/or disturbed sleep-wake cycles, is associated with a significantly increased risk of breast cancer and resistance to...

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Bibliografiska uppgifter
I publikationen:J Pineal Res
Huvudupphovsmän: Xiang, Shulin, Dauchy, Robert T., Hoffman, Aaron E., Pointer, David, Frasch, Tripp, Blask, David E., Hill, Steven M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6750268/
https://ncbi.nlm.nih.gov/pubmed/31077613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jpi.12586
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