Epigenetic inhibition of the tumor suppressor ARHI by light at night-induced circadian melatonin disruption mediates STAT3-driven paclitaxel resistance in breast cancer

Disruption of circadian time structure and suppression of circadian nocturnal melatonin (MLT) production by exposure to dim light at night (dLAN), as occurs with night shift work and/or disturbed sleep-wake cycles, is associated with a significantly increased risk of breast cancer and resistance to...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Pineal Res
Egile Nagusiak: Xiang, Shulin, Dauchy, Robert T., Hoffman, Aaron E., Pointer, David, Frasch, Tripp, Blask, David E., Hill, Steven M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6750268/
https://ncbi.nlm.nih.gov/pubmed/31077613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jpi.12586
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