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Opioid-Induced Signaling and Antinociception Are Modulated by the Recently Deorphanized Receptor, GPR171

ProSAAS is one of the most widely expressed proteins throughout the brain and was recently found to be upregulated in chronic fibromyalgia patients. BigLEN is a neuropeptide that is derived from ProSAAS and was recently discovered to be the endogenous ligand for the orphan G protein-coupled receptor...

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Bibliographische Detailangaben
Veröffentlicht in:J Pharmacol Exp Ther
Hauptverfasser: McDermott, Max V., Afrose, Leela, Gomes, Ivone, Devi, Lakshmi A., Bobeck, Erin N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6750184/
https://ncbi.nlm.nih.gov/pubmed/31308196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.119.259242
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