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Unraveling the effects of peroxiredoxin 2 nitration; role of C-terminal tyrosine 193
Peroxiredoxins (Prx) are enzymes that efficiently reduce hydroperoxides through active participation of cysteine residues (C(P), C(R)). The first step in catalysis, the reduction of peroxide substrate, is fast, 10(7) − 10(8) M(−1)s(−1) for human Prx2. In addition, the high intracellular concentratio...
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| Publicado en: | Free Radic Biol Med |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6749834/ https://ncbi.nlm.nih.gov/pubmed/31323313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2019.07.016 |
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