Hsp90 inhibitors enhance the antitumoral effect of osimertinib in parental and osimertinib-resistant non-small cell lung cancer cell lines

BACKGROUND: Osimertinib improve therapy for non-small cell lung cancer (NSCLC). However, invariable acquired resistance appears. METHODS: MTT assay was used to analyze cell viability. Protein expression and activation was detected by Western blotting. In addition, the effects of heat shock protein 9...

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Detalhes bibliográficos
Publicado no:Transl Lung Cancer Res
Main Authors: Codony-Servat, Jordi, Viteri, Santiago, Codony-Servat, Carles, Ito, Masaoki, Bracht, Jillian Willhelmina Paulina, Berenguer, Jordi, Chaib, Imane, Molina-Vila, Miguel Angel, Karachaliou, Niki, Rosell, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6749116/
https://ncbi.nlm.nih.gov/pubmed/31555510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr.2019.08.22
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