Integrin-linked kinase (ILK) and src homology 2 domain-containing phosphatase 2 (SHP2): Novel targets in EGFR-mutation positive non-small cell lung cancer (NSCLC)

BACKGROUND: The activation of multiple signaling pathways jeopardizes the clinical efficacy of EGFR tyrosine kinase inhibitors (TKIs) in EGFR-mutation positive non-small cell lung cancer (NSCLC). Integrin-linked kinase (ILK) regulates the interactions between tumor cells and extracellular environmen...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Karachaliou, Niki, Cardona, Andres Felipe, Bracht, Jillian Wilhelmina Paulina, Aldeguer, Erika, Drozdowskyj, Ana, Fernandez-Bruno, Manuel, Chaib, Imane, Berenguer, Jordi, Santarpia, Mariacarmela, Ito, Masaoki, Codony-Servat, Jordi, Rosell, Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6354556/
https://ncbi.nlm.nih.gov/pubmed/30473379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.11.036
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