Renoprotective effects of a novel cMet agonistic antibody on kidney fibrosis

Hepatocyte growth factor (HGF) and its receptor, cMet, activate biological pathways necessary for repair and regeneration following kidney injury. Because HGF is a highly unstable molecule in its biologically active form, we asked whether a monoclonal antibody (Ab) that displays full agonist activit...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Kim, Yong Chul, Lee, Junghun, An, Jung Nam, Kim, Jin Hyuk, Choi, Young-Wook, Li, Lilin, Kwon, Sang Ho, Lee, Mi-Young, Lee, Boeun, Jeong, Jae-Gyun, Yu, Seung-Shin, Lim, Chun Soo, Kim, Yon Su, Kim, Sunyoung, Yang, Seung Hee, Lee, Jung Pyo
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6749055/
https://ncbi.nlm.nih.gov/pubmed/31530851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49756-z
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