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PROSSTT: probabilistic simulation of single-cell RNA-seq data for complex differentiation processes

SUMMARY: Cellular lineage trees can be derived from single-cell RNA sequencing snapshots of differentiating cells. Currently, only datasets with simple topologies are available. To test and further develop tools for lineage tree reconstruction, we need test datasets with known complex topologies. PR...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Papadopoulos, Nikolaos, Gonzalo, Parra R, Söding, Johannes
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748774/
https://ncbi.nlm.nih.gov/pubmed/30715210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz078
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