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Copper Hydride Catalyzed Enantioselective Synthesis of Axially Chiral 1,3-Disubstituted Allenes

[Image: see text] The general enantioselective synthesis of axially chiral disubstituted allenes from prochiral starting materials remains a long-standing challenge in organic synthesis. Here, we report an efficient enantio- and chemoselective copper hydride catalyzed semireduction of conjugated eny...

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Publicado en:J Am Chem Soc
Autores principales: Bayeh-Romero, Liela, Buchwald, Stephen L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2019
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748664/
https://ncbi.nlm.nih.gov/pubmed/31423768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b07582
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