Pazopanib Exposure Relationship with Clinical Efficacy and Safety in the Adjuvant Treatment of Advanced Renal Cell Carcinoma

PURPOSE: PROTECT, a phase III randomized placebo-controlled study, evaluated pazopanib efficacy and safety in the adjuvant RCC setting. The relationship between pazopanib exposure (C(trough)) and efficacy and safety was evaluated. EXPERIMENTAL DESIGN: Evaluable steady-state blood trough concentratio...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Clin Cancer Res
Päätekijät: Sternberg, Cora N., Donskov, Frede, Haas, Naomi B., Doehn, Christian, Russo, Paul, Elmeliegy, Mohamed, Baneyx, Guillaume, Banerjee, Hiya, Aimone, Paola, Motzer, Robert J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748622/
https://ncbi.nlm.nih.gov/pubmed/29330204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-2652
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