HupA, the main undecaprenyl pyrophosphate and phosphatidylglycerol phosphate phosphatase in Helicobacter pylori is essential for colonization of the stomach

The biogenesis of bacterial cell-envelope polysaccharides requires the translocation, across the plasma membrane, of sugar sub-units that are produced inside the cytoplasm. To this end, the hydrophilic sugars are anchored to a lipid phosphate carrier (undecaprenyl phosphate (C(55)-P)), yielding memb...

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Udgivet i:PLoS Pathog
Main Authors: Gasiorowski, Elise, Auger, Rodolphe, Tian, Xudong, Hicham, Samia, Ecobichon, Chantal, Roure, Sophie, Douglass, Martin V., Trent, M. Stephen, Mengin-Lecreulx, Dominique, Touzé, Thierry, Boneca, Ivo Gomperts
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748449/
https://ncbi.nlm.nih.gov/pubmed/31487328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007972
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