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Periplasmic phosphorylation of lipid A is linked to the synthesis of undecaprenyl phosphate

One-third of the lipid A found in the Escherichia coli outer membrane contains an unsubstituted diphosphate unit at position 1 (lipid A 1-diphosphate). We now report an inner membrane enzyme, LpxT (YeiU), which specifically transfers a phosphate group to lipid A, forming the 1-diphosphate species. (...

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Detalhes bibliográficos
Main Authors: Touzé, Thierry, Tran, An X, Hankins, Jessica V, Mengin-Lecreulx, Dominique, Trent, M Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229476/
https://ncbi.nlm.nih.gov/pubmed/18047581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2007.06044.x
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