Function, clinical application, and strategies of Pre-mRNA splicing in cancer

Pre-mRNA splicing is a fundamental process that plays a considerable role in generating protein diversity. Pre-mRNA splicing is also the key to the pathology of numerous diseases, especially cancers. In this review, we discuss how aberrant splicing isoforms precisely regulate three basic functional...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Di, Cuixia, Syafrizayanti, Zhang, Qianjing, Chen, Yuhong, Wang, Yupei, Zhang, Xuetian, Liu, Yang, Sun, Chao, Zhang, Hong, Hoheisel, Jörg D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748147/
https://ncbi.nlm.nih.gov/pubmed/30464224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0231-3
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