PINK1-dependent mitophagy is driven by the UPS and can occur independently of LC3 conversion

The Parkinson’s disease (PD)-related ubiquitin ligase Parkin and mitochondrial kinase PINK1 function together in the clearance of damaged mitochondria. Upon mitochondrial depolarization, Parkin translocates to mitochondria in a PINK1-dependent manner to ubiquitinate outer mitochondrial membrane prot...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Rakovic, Aleksandar, Ziegler, Jonathan, Mårtensson, Christoph U., Prasuhn, Jannik, Shurkewitsch, Katharina, König, Peter, Paulson, Henry L., Klein, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748138/
https://ncbi.nlm.nih.gov/pubmed/30375512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0219-z
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados