Dclk1 in tuft cells promotes inflammation-driven epithelial restitution and mitigates chronic colitis

Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by defective intestinal barrier integrity toward the microbiota and epithelial damage. Double cortin-like kinase 1 (Dclk1), a marker of intestinal tuft cells, can regulate tissue regenerative responses, but its role in epi...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Yi, Jun, Bergstrom, Kirk, Fu, Jianxin, Shan, Xindi, McDaniel, J. Michael, McGee, Samuel, Qu, Dongfeng, Houchen, Courtney W., Liu, Xiaowei, Xia, Lijun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748088/
https://ncbi.nlm.nih.gov/pubmed/30478383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0237-x
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