Reconstitution of male germline cell specification from mouse embryonic stem cells using defined factors in vitro

In vitro induction of functional haploid cells from embryonic stem cells (ESCs) has been reported by several groups. However, these reports either involve complex induction process with undefined induction factors or show low-induction efficiency. Here, we report complete meiosis in vitro from ESCs...

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Udgivet i:Cell Death Differ
Main Authors: Li, Na, Ma, Wentao, Shen, Qiaoyan, Zhang, Mengfei, Du, Zhaoyu, Wu, Chongyang, Niu, Bowen, Liu, Wenqing, Hua, Jinlian
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748084/
https://ncbi.nlm.nih.gov/pubmed/30683919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0280-2
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