Reconstitution of male germline cell specification from mouse embryonic stem cells using defined factors in vitro

In vitro induction of functional haploid cells from embryonic stem cells (ESCs) has been reported by several groups. However, these reports either involve complex induction process with undefined induction factors or show low-induction efficiency. Here, we report complete meiosis in vitro from ESCs...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Differ
Prif Awduron: Li, Na, Ma, Wentao, Shen, Qiaoyan, Zhang, Mengfei, Du, Zhaoyu, Wu, Chongyang, Niu, Bowen, Liu, Wenqing, Hua, Jinlian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748084/
https://ncbi.nlm.nih.gov/pubmed/30683919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0280-2
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