Reconstitution of male germline cell specification from mouse embryonic stem cells using defined factors in vitro

In vitro induction of functional haploid cells from embryonic stem cells (ESCs) has been reported by several groups. However, these reports either involve complex induction process with undefined induction factors or show low-induction efficiency. Here, we report complete meiosis in vitro from ESCs...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Li, Na, Ma, Wentao, Shen, Qiaoyan, Zhang, Mengfei, Du, Zhaoyu, Wu, Chongyang, Niu, Bowen, Liu, Wenqing, Hua, Jinlian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748084/
https://ncbi.nlm.nih.gov/pubmed/30683919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0280-2
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