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Long noncoding RNA lncAIS downregulation in mesenchymal stem cells is implicated in the pathogenesis of adolescent idiopathic scoliosis

Adolescent idiopathic scoliosis (AIS) is a complex, three dimensional deformity of the spine that commonly occurs in pubescent girls. Abnormal osteogenic differentiation of mesenchymal stem cells (MSCs) is implicated in the pathogenesis of AIS. However, the biological roles of long noncoding RNAs (l...

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Détails bibliographiques
Publié dans:Cell Death Differ
Auteurs principaux: Zhuang, Qianyu, Ye, Buqing, Hui, Shangyi, Du, Ying, Zhao, Robert Chunhua, Li, Jing, Wu, Zhihong, Li, Na, Zhang, Yanbin, Li, Hongling, Wang, Shengru, Yang, Yang, Li, Shugang, Zhao, Hong, Fan, Zusen, Qiu, Guixing, Zhang, Jianguo
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748078/
https://ncbi.nlm.nih.gov/pubmed/30464226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0240-2
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