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Chromosome Territorial Organization Drives Efficient Protein Complex Formation: A Hypothesis

In eukaryotes, chromosomes often form a transcriptional kissing loop during interphase. We propose that these kissing loops facilitate the formation of protein complexes. mRNA transcripts from these loops could cluster together into phase-separated nuclear granules. Their export into the ER could be...

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Detalhes bibliográficos
Publicado no:Yale J Biol Med
Main Authors: Bera, Manindra, Kalyana Sundaram, Ramalingam Venkat
Formato: Artigo
Idioma:Inglês
Publicado em: YJBM 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6747946/
https://ncbi.nlm.nih.gov/pubmed/31543715
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