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Chromosome Territorial Organization Drives Efficient Protein Complex Formation: A Hypothesis
In eukaryotes, chromosomes often form a transcriptional kissing loop during interphase. We propose that these kissing loops facilitate the formation of protein complexes. mRNA transcripts from these loops could cluster together into phase-separated nuclear granules. Their export into the ER could be...
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| Publicado en: | Yale J Biol Med |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
YJBM
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6747946/ https://ncbi.nlm.nih.gov/pubmed/31543715 |
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