A Hyperstabilizing Mutation in the Base of the Ebola Virus Glycoprotein Acts at Multiple Steps To Abrogate Viral Entry

Ebola virus (EBOV) causes highly lethal disease outbreaks against which no FDA-approved countermeasures are available. Although many host factors exploited by EBOV for cell entry have been identified, including host cell surface phosphatidylserine receptors, endosomal cysteine proteases, and the lys...

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Publicat a:mBio
Autors principals: Fels, J. Maximilian, Spence, Jennifer S., Bortz, Robert H., Bornholdt, Zachary A., Chandran, Kartik
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6747718/
https://ncbi.nlm.nih.gov/pubmed/31289183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01408-19
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