The adaptive proline response in P. falciparum is independent of PfeIK1 and eIF2α signaling

We have previously identified the cytoplasmic prolyl tRNA synthetase in Plasmodium falciparum as the functional target of the natural product febrifugine and its synthetic analogue halofuginone (HFG), one of the most potent antimalarials discovered to date. However, our studies also discovered that...

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Publicat a:ACS Infect Dis
Autors principals: Fagbami, Lola, Deik, Amy A., Singh, Kritika, Santos, Sofia A., Herman, Jonathan D., Bopp, Selina E., Lukens, Amanda K., Clish, Clary B., Wirth, Dyann F., Mazitschek, Ralph
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6747701/
https://ncbi.nlm.nih.gov/pubmed/30773881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.8b00363
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