The adaptive proline response in P. falciparum is independent of PfeIK1 and eIF2α signaling

We have previously identified the cytoplasmic prolyl tRNA synthetase in Plasmodium falciparum as the functional target of the natural product febrifugine and its synthetic analogue halofuginone (HFG), one of the most potent antimalarials discovered to date. However, our studies also discovered that...

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Publicado no:ACS Infect Dis
Main Authors: Fagbami, Lola, Deik, Amy A., Singh, Kritika, Santos, Sofia A., Herman, Jonathan D., Bopp, Selina E., Lukens, Amanda K., Clish, Clary B., Wirth, Dyann F., Mazitschek, Ralph
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6747701/
https://ncbi.nlm.nih.gov/pubmed/30773881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.8b00363
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