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SILAC-Based Quantification of TGFBR2-Regulated Protein Expression in Extracellular Vesicles of Microsatellite Unstable Colorectal Cancers

Microsatellite unstable (MSI) colorectal cancers (CRCs) are characterized by mutational inactivation of Transforming Growth Factor Beta Receptor Type 2 (TGFBR2). TGFBR2-deficient CRCs present altered target gene and protein expression. Such cellular alterations modulate the content of CRC-derived ex...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Autores principales: Fricke, Fabia, Michalak, Malwina, Warnken, Uwe, Hausser, Ingrid, Schnölzer, Martina, Kopitz, Jürgen, Gebert, Johannes
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6747473/
https://ncbi.nlm.nih.gov/pubmed/31454892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20174162
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