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A new method for detection of tumor driver-dependent changes of protein sialylation in a colon cancer cell line reveals nectin-3 as TGFBR2 target

Protein-linked glycans play key roles in cell differentiation, cell–cell interactions, cell growth, adhesion and immune response. Aberrant glycosylation is a characteristic feature of tumor cells and is involved in tumor growth, escape from apoptosis, metastasis formation, and resistance to therapy....

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Lee, Jennifer, Warnken, Uwe, Schnölzer, Martina, Gebert, Johannes, Kopitz, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594667/
https://ncbi.nlm.nih.gov/pubmed/26177744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2741
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