Allyl isothiocyanate ameliorates lipid accumulation and inflammation in nonalcoholic fatty liver disease via the Sirt1/AMPK and NF-κB signaling pathways

BACKGROUND: Allyl isothiocyanate (AITC), a classic anti-inflammatory and antitumorigenic agent, was recently identified as a potential treatment for obesity and insulin resistance. However, little is known about its direct impact on the liver. AIM: To investigate the effect and underlying mechanism...

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Bibliografiske detaljer
Udgivet i:World J Gastroenterol
Main Authors: Li, Chun-Xiao, Gao, Jian-Guo, Wan, Xing-Yong, Chen, Yi, Xu, Cheng-Fu, Feng, Ze-Min, Zeng, Hang, Lin, Yi-Ming, Ma, Han, Xu, Ping, Yu, Chao-Hui, Li, You-Ming
Format: Artigo
Sprog:Inglês
Udgivet: Baishideng Publishing Group Inc 2019
Fag:
Basic Study
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6747284/
https://ncbi.nlm.nih.gov/pubmed/31558861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v25.i34.5120
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