Molecular Subtyping and Prognostic Assessment Based on Tumor Mutation Burden in Patients with Lung Adenocarcinomas

The distinct molecular subtypes of lung cancer are defined by monogenic biomarkers, such as EGFR, KRAS, and ALK rearrangement. Tumor mutation burden (TMB) is a potential biomarker for response to immunotherapy, which is one of the measures for genomic instability. The molecular subtyping based on TM...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Wang, Changzheng, Liang, Han, Lin, Cong, Li, Fuqiang, Xie, Guoyun, Qiao, Sitan, Shi, Xulian, Deng, Jianlian, Zhao, Xin, Wu, Kui, Zhang, Xiuqing
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6747282/
https://ncbi.nlm.nih.gov/pubmed/31480292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20174251
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