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Molecular Subtyping and Prognostic Assessment Based on Tumor Mutation Burden in Patients with Lung Adenocarcinomas

The distinct molecular subtypes of lung cancer are defined by monogenic biomarkers, such as EGFR, KRAS, and ALK rearrangement. Tumor mutation burden (TMB) is a potential biomarker for response to immunotherapy, which is one of the measures for genomic instability. The molecular subtyping based on TM...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Wang, Changzheng, Liang, Han, Lin, Cong, Li, Fuqiang, Xie, Guoyun, Qiao, Sitan, Shi, Xulian, Deng, Jianlian, Zhao, Xin, Wu, Kui, Zhang, Xiuqing
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6747282/
https://ncbi.nlm.nih.gov/pubmed/31480292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20174251
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