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Characterization of Tachyplesin Peptides and Their Cyclized Analogues to Improve Antimicrobial and Anticancer Properties

Tachyplesin I, II and III are host defense peptides from horseshoe crab species with antimicrobial and anticancer activities. They have an amphipathic β-hairpin structure, are highly positively-charged and differ by only one or two amino acid residues. In this study, we compared the structure and ac...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Vernen, Felicitas, Harvey, Peta J., Dias, Susana A., Veiga, Ana Salomé, Huang, Yen-Hua, Craik, David J., Lawrence, Nicole, Troeira Henriques, Sónia
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6747087/
https://ncbi.nlm.nih.gov/pubmed/31455019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20174184
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