Fatty Acid Inhibition Sensitizes Androgen-Dependent and -Independent Prostate Cancer to Radiotherapy via FASN/NF-κB Pathway

Elevated fatty acid synthase (FASN) has been reported in both androgen-dependent and -independent prostate cancers. Conventional treatment for prostate cancer is radiotherapy (RT); however, the following radiation-induced radioresistance often causes treatment failure. Upstream proteins of FASN such...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Chuang, Hui-Yen, Lee, Yen-Po, Lin, Wei-Chan, Lin, Yi-Hsien, Hwang, Jeng-Jong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6746859/
https://ncbi.nlm.nih.gov/pubmed/31527721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49486-2
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