Levosimendan pretreatment improves survival of septic rats after partial hepatectomy and suppresses iNOS induction in cytokine-stimulated hepatocytes

We evaluated the survival effects and biochemical profiles of levosimendan in septic rats after partial hepatectomy and investigated its effects in cultured hepatocytes. Thirty-two rats underwent 70% hepatectomy and were randomised equally into four groups, followed by lipopolysaccharide (LPS) injec...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sakaguchi, Tatsuma, Hashimoto, Yuki, Matsushima, Hideyuki, Hishikawa, Hidehiko, Nishizawa, Mikio, Okumura, Tadayoshi, Kaibori, Masaki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6746814/
https://ncbi.nlm.nih.gov/pubmed/31527618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48792-z
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