A Simple RNA Target Capture NGS Strategy for Fusion Genes Assessment in the Diagnostics of Pediatric B-cell Acute Lymphoblastic Leukemia

Acute lymphoblastic leukemia (ALL) is the most frequent pediatric cancer. Fusion genes are hallmarks of ALL, and they are used as biomarkers for risk stratification as well as targets for precision medicine. Hence, clinical diagnostics pursues broad and comprehensive strategies for accurate discover...

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Publicado en:Hemasphere
Main Authors: Grioni, Andrea, Fazio, Grazia, Rigamonti, Silvia, Bystry, Vojtech, Daniele, Giulia, Dostalova, Zuzana, Quadri, Manuel, Saitta, Claudia, Silvestri, Daniela, Songia, Simona, Storlazzi, Clelia T., Biondi, Andrea, Darzentas, Nikos, Cazzaniga, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado: Wolters Kluwer Health 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6746019/
https://ncbi.nlm.nih.gov/pubmed/31723839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HS9.0000000000000250
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