What is the relevance of Ikaros gene deletions as a prognostic marker in pediatric Philadelphia-negative B-cell precursor acute lymphoblastic leukemia?

New prognostic markers are needed for upfront identification of patients with acute lymphocytic leukemia with a high risk of relapse or who are not likely to respond to the most aggressive chemotherapy. We focused our analysis on Ikaros (IKZF1) gene deletions in a homogeneous cohort of 410 pediatric...

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Hlavní autoři: Palmi, Chiara, Valsecchi, Maria Grazia, Longinotti, Giulia, Silvestri, Daniela, Carrino, Valentina, Conter, Valentino, Basso, Giuseppe, Biondi, Andrea, Kronnie, Geertruy Te, Cazzaniga, Giovanni
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2013
Témata:
Original Articles and Brief Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729902/
https://ncbi.nlm.nih.gov/pubmed/23585525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.075432
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